History:
Grapes appear to have originated in the Mediterranean regions of southern Europe and Middle East, thriving in deep, moist, humus-rich, neutral-to-alkaline soil in sun and warm climates; and the grape's hardiness varies according to the cultivars. Grapes were first cultivated near the Caspian Sea, and their use as food and drink had spread throughout the Mediterranean world before The Bible was written. They were cultivated in Egypt over four thousand years ago, and even the ancient Greeks knew that wine possessed wonderful Health Benefits. Wine is the fermented juice of grapes, and it has been used in various cultures for almost five thousand years.

Egyptian records dating from 2500 B.C. refer to wines, and there are frequent references to wine in the Old Testament. Wine was also used by early Minoan and Etruscan civilizations, and we can thank the Roman army for introducing the rootstocks and winemaking throughout Europe as they created an expanding Roman Empire. Centuries later the role of wine for sacramental use in Christian churches helped to maintain the industry after the fall of the Roman Empire. Modern science has now confirmed the Health Benefits included in occasional Red Wine consumption, and although you may not be enjoying the taste of this wondrous gift of nature, you will enjoy a convenient way to enjoy its many healthy benefits (without having to relinquish the keys to your car) in this easy supplement. Red Wine Extracts (not white) possess high concentrations of proanthocyanidins that confer high antioxidant and free radical benefits, as well as phenolic and polyphenolic compounds (including catechin, Quercetin, resveratrol, et al) that combat platelet aggregation (clotting) in the blood.

Conditions:
With regard to good coronary health, Red Wine Extract from Grapeseed has become a popular supplement for preventing Heart disease and arteriosclerosis. Numerous studies now say that the level of antioxidants may be a more significant factor than cholesterol levels in determining the risk of developing Heart disease.

The powerful antioxidants in Red Wine Extract are said to help prevent the oxidation of cholesterol that ultimately leads to the process of arteriosclerosis, and the high flavonoid content in Red Wine Extract appears capable of significantly reducing the risk of heart attack or Stroke. Red Wine Extract is said to help reduce platelet aggregation (clotting) in the blood, thereby also reducing the risk of arteriosclerosis, Stroke and heart attacks. Moreover, it appears to raise the levels of high-density lipoproteins (HDLs or "good" cholesterol) in the blood, while decreasing the low-density lipoproteins (LDLs, or "bad" cholesterol) and thereby help to prevent heart attacks and strokes.

The HDL is said to help clear the "bad" cholesterol from the arterial walls and help eliminate it from the body. This action also helps to promote better Circulation of blood throughout the body, especially to the heart.

For good vascular health, Red Wine Extract is considered the best herbal supplement that will maintain the health of capillaries, through which the blood delivers nutrients to individual cells and carries away waste products.
Red Wine Extract is also said to improve peripheral blood Circulation, resulting in less pain and swelling in arms, ankles and legs and fewer nighttime cramps. Use of Red Wine Extract is thought to relieve numbness and tingling, as well as Varicose veins. When the walls of small blood vessels weaken, the fluids they transport leak out, causing swelling, and OPCs strengthen capillary walls by blocking the degradation of the two proteins that give them strength and elasticity, collagen and elastin. This action stops Edema and swelling.

Red Wine Extract is believed to significantly improve blood Circulation, which benefits both cardiac and cerebral function. Furthermore, because OPCs are able to cross the blood-brain barrier, they can protect the brain and spinal nerves against free radical damage. Recent studies indicate that Red Wine Extract's compounds (OPCs) may also be helpful in inhibiting Alzheimer's disease and dementia and possibly improving cognitive and brain function (particularly in women).

As one of the finest antioxidants found in nature, Red Wine Extract from Grapeseed supports the immune system and works to combat free radical damage to cells and tissue and defend the body against serious malignant disease and infection. This herbal supplement contains an important source of nature's most potent antioxidants, tannin compounds called proanthocyanidins (also called OPCs for oligomeric procyanidins or PCOs for procyanidolic oligomers) that provide a high degree of antioxidant capacity, which fight free radical damage in the body.

These compounds allow the body's cells to absorb vitamin C, which is helpful in protecting cells from the free radicals that can bind to and destroy cellular compounds. Such qualities are believed to be helpful in building the immune system and fighting invasive material and other infections.

They are classified as flavonols, and the way in which these versatile healing compounds are distinct from flavonoids is their simple chemical structure, which allows them to be readily absorbed into the bloodstream. They work actively against fat-soluble and water-soluble oxidants, thus protecting the cells from damage. OPCs may also be derived from Pine Bark (the original source) and are present in Pomegranate, Hops, various flowers, fruits, berries, nuts and beans. Clinical tests suggest that OPCs may be as much as fifty times more potent than vitamin E and twenty times more potent than vitamin C in terms of bioavailabile antioxidant activity. Studies have shown that Red Wine Extract not only enhances the development of normal cells, but may also inhibit abnormal cell growth.

Macular degeneration may be slowed by the use of Red Wine Extract, and it may also reduce myopia and improve vision that is stressed by computer screens or glare.

Red Wine Extract's OPCs are said to promote tissue regeneration, strengthen and repair connective tissue, enhance collagen production, revitalize ageing skin and promote tissue elasticity, all of which also helps to reduce the tendency to bruise easily and increases the healing of injuries.

Test tube research has shown that the polyphenols in Red Wine Extract inhibit the growth of the Streptococcus mutans Bacteria that causes tooth decay.

Red Wine Extract is said to reduce histamine production, thus moderating allergic and inflammatory responses, and this action has helped many allergy sufferers.